Tumor Lysis Syndrome: Uric Acid Crisis

Oncologic emergency where cancer treatment destroys a large number of cells rapidly, releasing intracellular potassium, phosphate, and nucleic acids into circulation. Nucleic acids are metabolized to uric acid, which precipitates in renal tubules, causing acute kidney injury (AKI). Connect Tumor Lysis Syndrome: Uric Acid Crisis to bedside cues you will reassess first: vitals trends, work of breathing, perfusion, mentation, and pain or ischemic equivalents when relevant. Boards reward recognizing when subtle instability outweighs reassurance, then selecting nursing actions that protect airway, circulation, and neurologic status before routine tasks.