Pathophysiology
Clinical meaning
A myocardial infarction occurs when coronary artery occlusion (usually from plaque rupture and thrombus formation) interrupts blood supply to the myocardium. Without oxygen, myocytes undergo irreversible injury within 20-40 minutes, releasing cardiac biomarkers (troponin, CK-MB) into the bloodstream. The nurse assists with monitoring, administers medications as ordered, and reports changes in the patient's condition.
